1 Result for "

ONO7684

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ONO7684" in MCE Product Catalog:

Cat. No.: HY-183409
CAS No.: 1941243-22-6
Synonyms: ONO-5450598
Target:  

Factor Xa

Research Areas:  

Cardiovascular Disease

ONO-7684 (ONO-5450598) is an orally active coagulation factor XIa (FXIa) inhibitor with a Ki value of 2 nM against human FXIa. ONO-7684 inhibits human FXIa in a competitive and reversible manner, reduces factor XI coagulation activity, prolongs activated partial thromboplastin time in a dose-dependent manner, and exerts no significant effects on PT/INR and the activity of related serine proteases. ONO-7684 exerts antithrombotic effects in vivo without prolonging bleeding time. ONO-7684 can be used in studies related to thromboembolic diseases .
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