1 Result for "

OP3136

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "OP3136" in MCE Product Catalog:

Cat. No.: HY-182468
CAS No.: 3056105-63-3
Research Areas:  

Cancer

OP-3136 is an orally active, highly selective inhibitor of KAT6A and KAT6B. OP-3136 inhibits the proliferation of prostate cancer, ovarian cancer and non-small cell lung cancer cells that express or overexpress KAT6A. OP-3136 reduces the proliferative capacity of cancer cells and suppresses cell growth in ER + breast cancer cell models with KAT6 overexpression. OP-3136 induces tumor regression and inhibits tumor growth in an ovarian cancer xenograft model in immunodeficient mice. OP-3136 inhibits tumor growth in a non-small cell lung cancer xenograft model in immunodeficient mice. OP-3136 can be used in research related to HR +/HER 2- breast cancer, prostate cancer, ovarian cancer and non-small cell lung cancer (NSCLC) .
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