1 Result for "

OPC33540

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "OPC33540" in MCE Product Catalog:

Cat. No.: HY-112631
CAS No.: 189362-27-4
Research Areas:  

Cardiovascular Disease

OPC-33540 is a highly selective and competitive PDE3 inhibitor with IC50 values of 0.32 nM (PDE3A) and 1.5 nM (PDE3B). OPC-33540 exhibits IC50s against PDE1, PDE2, PDE4, PDE5, and PDE7 of 42.9, 52.3, 100.8, 2.5, and 51.3 μM, respectively. OPC-33540 significantly enhances cAMP accumulation in platelets and effectively inhibits thrombin-induced platelet aggregation. OPC-33540 can be used in antithrombotic studies .
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