1 Result for "

ORS14

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ORS14" in MCE Product Catalog:

Cat. No.: HY-184689
CAS No.: 1311892-52-0
Target:  

LILRB

Research Areas:  

Cancer

ORS-14 is a LILRB4/ILT3 ligand with a Kd of 85.2 nM for human receptors. ORS-14 blocks SCG2-mediated LILRB4 signaling pathway, reverses SCG2-mediated immunosuppression, restores cytokine production, reduces tumor cell viability, recovers cytotoxic T cell function, and increases the frequency of granzyme B + CD8 + T cells. ORS-14 can be used in research related to colorectal cancer and acute myeloid leukemia .
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