1 Result for "

P-SETDB1-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "P-SETDB1-4" in MCE Product Catalog:

Cat. No.: HY-184362
Research Areas:  

Cancer

P-SETDB1-4 is a SETDB1 PROTAC degrader with a Kd of 86 nM. P-SETDB1-4 recruits CRBN to SETDB1, induces proteasome-dependent degradation of SETDB1, and forms a ternary complex with CRBN to achieve targeted degradation. P-SETDB1-4 reduces DNA synthesis. P-SETDB1-4 exhibits anticancer activity against breast cancer. P-SETDB1-4 can be used in breast cancer-related research .
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