2 Results for "

P7C3-S243

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "P7C3-S243" in MCE Product Catalog:

Cat. No.: HY-186105
CAS No.: 1421622-85-6
Target:  

NAMPT

Research Areas:  

Neurological Disease

P7C3-S243 is a brain-penetrant P7C3 class of neuroprotective agent. P7C3-S243 augments synthesis of nicotinamide adenine dinucleotide through activation of the metabolic enzyme nicotinamide phosphoribosyltransferase. P7C3-S243 shows potent neuroprotective efficacy in parkinson’s disease mice models. P7C3-S243 can be used for the research of parkinson’s disease .
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Cat. No.: HY-186105A
CAS No.: 1597443-57-6
Research Areas:  

Neurological Disease

(-)-P7C3-S243 is an orally active, blood-brain barrier permeable neuroprotective agent. (-)-P7C3-S243 binds to μ-opioid Receptor and TSPO. (-)-P7C3-S243 inhibits the premature apoptosis death of newborn hippocampal neurons, protects mature nigral dopaminergic neurons, promotes neuronal survival and prevents cognitive impairment. (-)-P7C3-S243 ameliorates depression-like behaviors in rat models. (-)-P7C3-S243 is applicable to research related to Parkinson's disease and Alzheimer's disease .
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