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Results for "

PC3 PIP

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Biochemical Assay Reagents

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W054292
    tert-Butyl-DCL

    (OtBu)KuE(OtBu)2

    		 PSMA Cancer
    Tert-Butyl-DCL is a PSMA inhibitor. Tert-Butyl-DCL Tert-Butyl-DCL can be used in the research of prostate cancer .
    tert-Butyl-DCL
  • HY-172366
    BQ0413

    		PSMA Cancer
    BQ0413 exhibits good affinity to PSMA with a KD of 89 pM. BQ0413 exhibits good uptake and internalization property with an internalization rate of 44% in PC3-pip cell. BQ0413 can be used as tumor imaging agent when labeled with 99mTc .
    BQ0413
  • HY-163683
    EB-PSMA-617

    		Radionuclide-Drug Conjugates (RDCs) PSMA Cancer
    EB-PSMA-617 is a modified form of PSMA-617 that has enhanced pharmacokinetic properties by conjugating it to Evans Blue (EB) to extend its circulation half-life to improve prostate tumor uptake and radiotherapy efficacy. In preclinical studies using PC3-PIP-loaded mice, EB-PSMA-617 demonstrated prolonged blood half-life, increased accumulation in PSMA-positive tumors, and successful tumor elimination with lower radioactivity .
    EB-PSMA-617
  • HY-181830
    Atz-L5

    		PD-1/PD-L1 PSMA LYTACs Cancer
    Atz-L5 is a PD-L1 PTAC (PSMA-targeted chimera) degrader (DC50: 18 pM in PC3-PIP cells; 2 pM in LNCaP cells) and LYTAC. Atz-L5 promotes lysosomal degradation of PD-L1 in PSMA-positive prostate cancer cells. Atz-L5 is applicable to the research of prostate cancer .
    Atz-L5

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