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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
PD 305
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "PD 305" in MCE Product Catalog:
Cat. No.: HY-183937A
Target:
Research Areas:
PD-305 is a selective PTPN2 PROTAC degrader, with DC50 values of 0.25 nM and 5.11 nM against PTPN2 and PTPN1, respectively. PD-305 enhances IFN-γ-induced STAT1 phosphorylation, inhibits the proliferation of IFN-γ-stimulated colorectal cancer cells, promotes CD8 + T cell activation, enhances the tumor-killing activity of T cells, and suppresses tumor growth in mouse models. PD-305 can be used for the research of colorectal cancer .
Cat. No.: HY-184259
Research Areas:
PTPN2 ligand 4 is a PTPN2 ligand and can be used for the synthesis of PROTACs, such as PD-305 (HY-183937) .
Cat. No.: HY-184258
CAS No.: 2504233-60-5
Target:
Research Areas:
CRBN ligand-905 is a naphtholactam-based CRBN E3 ligase ligand used in the design of PTPN2 PROTAC degraders PD-305 (HY-183937) .
Cat. No.: HY-184260
Research Areas:
CRBN ligand-905-piperidine-cyclobutane-acid is an E3 ligase ligand-linker conjugate, consisting of a ligand based on CRBN and a linker, and can be used for the synthesis of PROTACs, such as PD-305 (HY-183937).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
