1 Result for "

PDGFR1β

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "PDGFR1β" in MCE Product Catalog:

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Cat. No.: HY-111090
CAS No.: 929095-23-8
Research Areas:  

Cancer

GSK461364 analogue 1 is a thiophene-based PLK1 inhibitor with a PLK1 IC50 of 2 nM and a PLK3 IC50 of 630 nM. GSK461364 analogue 1 also acts as an inhibitor of Nek2 kinase (IC50: 21 nM). GSK461364 analogue 1 has a solubility of ≥190 μM in pH 7.4 PBS and a human plasma protein binding rate of 91.5%. GSK461364 analogue 1 can be used in studies related to colon cancer, lung cancer, breast cancer and ovarian cancer [1].
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