1 Result for "

PDI-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PDI-IN-4" in MCE Product Catalog:

Cat. No.: HY-170655
CAS No.: 3104129-77-0
Target:  

PDI Integrin

Research Areas:  

Cardiovascular Disease

PDI-IN-4 is a highly selective inhibitor of human PDI (IC50=0.48 μM) with no significant cytotoxicity. PDI-IN-4 binds to PDI in a reversible manner, not only forming a covalent bond with the Cys400 residue but also engaging in hydrophobic interactions with other residues. By inhibiting the activation of GPIIb/IIIa, PDI-IN-4 effectively blocks platelet aggregation and thrombus formation. PDI-IN-4 can serve as an important tool reagent for thrombosis-related research .
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