1 Result for "

PKZ18

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PKZ18" in MCE Product Catalog:

Cat. No.: HY-169810
CAS No.: 849658-87-3
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

PKZ18 is an antibiotic and inhibits bacterial growth, with MIC values of 32-64 μg/mL against most Gram-positive bacteria. PKZ18 inhibits in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria and directly reduces T-box transcriptional read-through of the associated genes. PKZ18 prevents the codon-anticodon reading required for tRNA binding and is refractory to resistance .
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