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PLAGL2

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS10645

    Small Interfering RNA (siRNA) Others

    PLAGL2 Human Pre-designed siRNA Set A contains three designed siRNAs for PLAGL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PLAGL2 Human Pre-designed siRNA Set A
    PLAGL2 Human Pre-designed siRNA Set A
  • HY-180281

    Zinc Finger Protein Apoptosis PI3K Akt Cancer
    PLAGL2-IN-1 is a inhibitor of pleiomorphic adenoma-like protein 2 (PLAGL2) with a Kd of 2.23 µM. PLAGL2-IN-1 suppresses PLAGL2 transcriptional activity, induces G0/G1 cell cycle arrest, and apoptosis, thereby inhibiting hepatocellular carcinoma (HCC) cell proliferation. PLAGL2-IN-1 disrupts extracellular matrix organization and suppresses the PI3K-AKT pathway by reducing AKT phosphorylation. PLAGL2-IN-1 inhibits tumor growth in an HCCLM3 xenograft mouse model. PLAGL2-IN-1 can be used for the research of HCC .
    PLAGL2-IN-1

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