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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
PNO1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "PNO1" in MCE Product Catalog:
Cat. No.: HY-D3351
CAS No.: 2668963-61-7
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PNO1 is a fluorescent probe for pulmonary fibrosis detection. The detection mechanism of PNO1 relies on sensing upregulated nitric oxide (NO) in the pulmonary fibrosis (PF) microenvironment. PNO1 contains an aniline group that reacts with NO or its derivatives under acidic conditions to form an N-nitrosylated intermediate, which is subsequently converted into a diazonium salt and undergoes deamination, eliminating the intramolecular electron transfer quenching effect and triggering a fluorescence turn-on response. The excitation wavelength of PNO1 includes 545 nm in in vitro solution studies, while an excitation range of 520-550 nm is used for cell, tissue and in vivo imaging; its emission wavelength centers at 572 nm in the unreacted state, and shifts to 559 nm with enhanced fluorescence intensity upon binding to NO. PNO1 can be used for pulmonary fibrosis research [1].
Cat. No.: HY-RS10787
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PNO1 Human Pre-designed siRNA Set A contains three designed siRNAs for PNO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20797
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Pno1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pno1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27311
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Pno1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pno1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702824
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PNO1; RNA-Binding Protein PNO1; Prev. KHRBP1; Partner Of NOB1 Homolog (S. Cerevisiae); RRP20; KH-Type RNA Binding Protein 1; KH-Type RNA-Binding Protein 1; Partner Of NOB1; Partner Of NOB1 Homolog; RNA Binding Protein
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
