1 Result for "

PU-11

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PU-11" in MCE Product Catalog:

Cat. No.: HY-116053
CAS No.: 1454619-18-1
Target:  

HSP

Research Areas:  

Neurological Disease

PU-11 is a Hsp90α/Hsp90β inhibitor with IC50 values of 18.6 μM and 89.8 μM and Kd values of 2 and 4.2 μM. PU-11 binds to the ATP-binding pocket of Hsp90α and Hsp90β and displays selective binding preference for Hsp90α over Hsp90β, mediated by the nonconserved Hsp90α Ser52 residue. PU-11 can be used for the research of neurodegenerative disorders .
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