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PUGNAc

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108241
    (Z)-PUGNAc
    4 Publications Verification

    		 OGA Metabolic Disease
    (Z)-PUGNAc is a potent O-GlcNAcase inhibitor. (Z)-PUGNAc is a vastly more potent inhibitor of O-GlcNAcase than the E form .
    (Z)-PUGNAc
  • HY-108241R
    (Z)-PUGNAc (Standard)

    		OGA Reference Standards Metabolic Disease
    (Z)-PUGNAc (Standard) is the analytical standard of (Z)-PUGNAc (HY-108241). This product is intended for research and analytical applications. (Z)-PUGNAc is a potent O-GlcNAcase inhibitor. (Z)-PUGNAc is a vastly more potent inhibitor of O-GlcNAcase than the E form .
    (Z)-PUGNAc (Standard)
  • HY-108241A
    Galacto-PUGNAc

    		Glycosidase Neurological Disease
    Galacto-PUGNAc is a selective competitive inhibitor of lysosomal β-hexosaminidases (HEX), with Ki values of 51 and 18 nM, for hHEXA and hHEXB, respectively. Galacto-PUGNAc elevates GM2 ganglioside levels in neuroblastoma cells. Galacto-PUGNAc can be used for the research of neurodegenerative disorders .
    Galacto-PUGNAc
  • HY-E71360
    O-GlcNAcase, Clostridium perfringens

    		Glycosidase Others
    O-GlcNAcase, Clostridium perfringens is a glycosidase derived from Clostridium perfringens, which functions in bacterial nutrient metabolism, host interaction and virulence regulation. O-GlcNAcase is a core enzyme in the cellular signal regulatory network and serves as a key target for various major and chronic diseases. O-GlcNAcase, Clostridium perfringens can be used for basic research and drug development of O-GlcNAcase due to its high conservation in catalytic mechanism and structure with human-derived enzymes .
    O-GlcNAcase, Clostridium perfringens

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