1 Result for "

Pentabromophenol

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Pentabromophenol" in MCE Product Catalog:

Cat. No.: HY-W105318
CAS No.: 608-71-9
Synonyms: PBP
Target:  

TGF-beta/Smad Apoptosis

Research Areas:  

Cancer

Pentabromophenol (PBP) is a brominated flame retardant (BFR) widely used in various consumer products to reduce the flammability of materials used in different utility items. Pentabromophenol can accelerate the degradation of transforming growth factor-β (TGF-β) receptors by promoting clathrin-mediated endocytosis, thereby inhibiting the TGF-β signaling pathway. Additionally, Pentabromophenol can also induce apoptosis in peripheral blood mononuclear cells (PBMCs) .
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