1 Result for "

Perforin-IN-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Perforin-IN-3" in MCE Product Catalog:

Cat. No.: HY-W989139
CAS No.: 178970-88-2
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Perforin-IN-3 is a specific perforin inhibitor that blocks perforin-mediated lytic pore formation and subsequent cell lysis. Perforin-IN-3 potently inhibits the killing effect of NK cells on target cells such as leukemia cells, without interfering with FasL- or TRAIL-mediated cell death pathways. Perforin-IN-3 has no effect on pneumolysin and can be used to study autoimmune diseases, allograft rejection, graft-versus-host disease, and familial hemophagocytic lymphohistiocytosis .
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