1 Result for "

Ponalrestat (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Ponalrestat (Standard)" in MCE Product Catalog:

Cat. No.: HY-106697R
CAS No.: 72702-95-5
Synonyms: ICI 128436 (Standard)
Research Areas:  

Metabolic Disease

Ponalrestat (Standard) (ICI 128436 (Standard)) is the analytical standard of Ponalrestat (HY-106697). This product is intended for research and analytical applications. Ponalrestat (ICI 128436) is an orally active, selective and noncompetitive aldose reductase (AKR1B1; ALR) inhibitor. Ponalrestat selectively inhibits ALR2 (Ki=7.7 nM) over ALR1 (Ki=60 μM). Ponalrestat inhibits the conversion of glucose to sorbitol .
loading...
    loading...