1 Result for "

Pro-PTX

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Pro-PTX" in MCE Product Catalog:

Cat. No.: HY-177482
CAS No.: 3011748-20-9
Target:  

Drug Intermediate

Research Areas:  

Neurological Disease Cancer

Pro-PTX is a Pd-sensitive Paclitaxel (HY-B0015) prodrug with anticancer activity. Pro-PTX triggers intramolecular cyclization via Pd-catalyzed depropargylation to release active Paclitaxel (HY-B0015) and a non-toxic byproduct. Pro-PTX exhibits low cytotoxicity and antiproliferative activity in cancer cells and non-cancerous human cerebrovascular pericytes. Pro-PTX is applicable for research related to non-small cell lung cancer, glioblastoma and lung cancer .
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