1 Result for "

Protofibrillar

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Protofibrillar" in MCE Product Catalog:

Cat. No.: HY-P991654

Target:  

Amyloid-β

Research Areas:  

Neurological Disease

SAR228810 is a humanized IgG4 monoclonal antibody inhibitor targeting amyloid β (Aβ) with a KD? of ?0.43 ?nM for protofibrillar Aβ over monomeric Aβ. SAR228810 significantly inhibits the brain amyloid plaque formation and oligomer-induced synaptic dysfunction and neurite loss. SAR228810 has significant protection against Aβ-mediated neuritotoxicity. MINT1526A can be used for Alzheimer’s disease imaging and immunotherapy research .
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