1 Result for "

QNZ46

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "QNZ46" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-15703
CAS No.: 1237744-13-6
Purity:  99.46%
Target:  

iGluR

Research Areas:  

Neurological Disease

QNZ46 is a highly selective noncompetitive NMDA receptor antagonist targeting GluN2C/D (IC50=3.9 μM), GluN1/GluN2C (IC50=7.1 μM), and GluN1/GluN2D (IC50=182 μM) subunits. QNZ46 inhibits glutamate-mediated calcium influx, thereby blocking excitotoxicity. QNZ46 is membrane permeable and can cross the blood-brain barrier, where it inhibits myelin damage and axonal degeneration .
loading...
    loading...