3 Results for "

R106056

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "R106056" in MCE Product Catalog:

Cat. No.: HY-106181
CAS No.: 185428-18-6
Purity:  98.59%
Synonyms: R-106056
Target:  

PPAR

Rivoglitazone (R-106056) is an orally active, selective PPARγ agonist with an EC50 of 0.22 μM for hPPARγ. Rivoglitazone regulates fatty acid storage and uptake, glucose homeostasis, and cardiac glucose/fatty acid metabolism. Rivoglitazone reduces levels of hyperglycemia, hyperinsulinemia, and hypertriglyceridemia, decreases hepatic glucose production, and accelerates plasma triglyceride clearance. Rivoglitazone induces a reduction in glycated hemoglobin A1C, while causing peripheral edema and weight gain. Rivoglitazone can be used in research related to type 2 diabetes .
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Cat. No.: HY-106181A
CAS No.: 299176-11-7
Synonyms: R-106056 hydrochloride
Target:  

PPAR

Research Areas:  

Metabolic Disease

Rivoglitazone hydrochloride (R-106056 hydrochloride) is a peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist. Rivoglitazone hydrochloride (R-106056 hydrochloride) exerts its anti-diabetic effect by activating PPARγ to regulate the expression of a large number of genes related to lipid and glucose metabolism. Rivoglitazone hydrochloride (R-106056 hydrochloride) can be used to study insulin secretion and insulin resistance in animal models of diabetes .
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Cat. No.: HY-106181R
CAS No.: 185428-18-6
Synonyms: R-106056 (Standard)
Research Areas:  

Metabolic Disease

Rivoglitazone (Standard) is the analytical standard of Rivoglitazone (HY-106181). This product is intended for research and analytical applications. Rivoglitazone is a thiazolidinedione-derivative PPARγ agonist for the research of type 2 diabetes mellitus.
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