1 Result for "

R9-caPep

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "R9-caPep" in MCE Product Catalog:

Cat. No.: HY-183488
CAS No.: 1207092-73-6
Synonyms: RRRRRRRRRCCLGIPEQEY
Target:  

Apoptosis PARP

Research Areas:  

Cancer

R9-caPep (RRRRRRRRRCCLGIPEQEY) is a cell-penetrating peptide derived from proliferating cell nuclear antigen (PCNA). R9-caPep selectively blocks the interactions between PCNA and FEN1, as well as between PCNA and LIGI, while preserving the binding of POLD3 to PCNA. R9-caPep interferes with DNA synthesis and homologous recombination-mediated double-strand DNA break repair, inducing S-phase arrest, DNA damage accumulation, and apoptosis. R9-caPep inhibits the growth of tumor volume and weight of neuroblastoma in nude mice . R9-caPep can be used in research related to neuroblastoma and triple-negative breast cancer .
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