1 Result for "

RBN013209

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RBN013209" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-144987
CAS No.: 2597933-17-8
Purity:  98.84%
Target:  

CD38 LAG-3 Tim3 PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

RBN013209 is an orally active small molecule inhibitor of CD38 with an IC50 of 0.01 to 0.1 μM for human CD38. RBN013209 prevents the conversion of extracellular NAD + to ADPR or cADPR in tumor cells and PBMCs. RBN013209 can be used in the study of tumor. In addition, RBN013209 enables CAR-T cells to maintain the naive state and central memory state, and decreases the expression of cell activation markers and exhaustion-related inhibitory receptors .
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