1 Result for "

ROR1-IN-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ROR1-IN-3" in MCE Product Catalog:

Cat. No.: HY-174382
Target:  

Akt mTOR NF-κB ROR Apoptosis

Research Areas:  

Cancer

ROR1-IN-3 (Compound 24d) is a potent and highly selective ROR1 kinase inhibitor (IC50 = 17.6 nM). ROR1-IN-3 demonstrates robust antitumor activity and inhibitory effect against ROR1 both in vitro and in vivo. ROR1-IN-3 has robust antiproliferative efficacy in vitro and in vivo. ROR1-IN-3 induces apoptosis in cancer cell lines. ROR1-IN-3 inhibits ROR1 downstream AKT/mTOR and NF-κB signaling pathway. ROR1-IN-3 can be studied in antitumor research .
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