3 Results for "

Rebemadlin

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Rebemadlin" in MCE Product Catalog:

74
74 Cited Publications
Cat. No.: HY-10029
CAS No.: 675576-98-4
Purity:  99.00%
Synonyms: Rebemadlin
Research Areas:  

Cancer

Nutlin-3a (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53 wild-type ovarian carcinomas .
loading...
    loading...
Cat. No.: HY-10029A
CAS No.: 890090-75-2
Synonyms: (Rac)-Rebemadlin
Research Areas:  

Cancer

(Rac)-Nutlin-3 (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). (Rac)-Nutlin-3 inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. (Rac)-Nutlin-3 has the potential for the study of TP53 wild-type ovarian carcinomas .
loading...
    loading...
Cat. No.: HY-10029R
CAS No.: 675576-98-4
Synonyms: Rebemadlin (Standard)
Nutlin-3a (Standard) is the analytical standard of Nutlin-3a (HY-10029). This product is intended for research and analytical applications. Nutlin-3a (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53 wild-type ovarian carcinomas .
loading...
    loading...