1 Result for "

Replication-defective virus

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Replication-defective virus" in MCE Product Catalog:

Cat. No.: HY-180785
CAS No.: 932311-85-8
Target:  

Orthopoxvirus

Research Areas:  

Infection

G243-1720 is a potent, orally active, broad-spectrum anti-orthopoxvirus agent that functions by targeting the OPG57 (F13) protein and inducing its dimerization. G243-1720 effectively inhibits the replication of various poxviruses, but has no inhibitory effect on non-poxviruses. G243-1720 prevents the formation of extracellular membrane virus particles and the spread between cells. G243-1720 significantly reduces the viral load of monkeypox virus (MPXV) in the lungs of mice
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