3 Results for "

Rofecoxib

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Rofecoxib" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-17372
CAS No.: 162011-90-7
Synonyms: MK 966
Target:  

COX

Research Areas:  

Inflammation/Immunology Cancer

Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells).
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Cat. No.: HY-17372S
CAS No.: 544684-93-7
Rofecoxib-d5 is the deuterium labeled Rofecoxib. Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells) .
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Cat. No.: HY-17372R
CAS No.: 162011-90-7
Synonyms: MK 966 (Standard)
Target:  

Reference Standards COX

Research Areas:  

Inflammation/Immunology Cancer

Rofecoxib (Standard) is the analytical standard of Rofecoxib. This product is intended for research and analytical applications. Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells).
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