5 Results for "

Rsp5/Nedd4

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Rsp5/Nedd4" in MCE Product Catalog:

Cat. No.: HY-110174
CAS No.: 1504588-00-4
Purity:  99.69%
Target:  

α-synuclein

Research Areas:  

Neurological Disease

NAB2 is a neuroprotectant that targets the small GTPase Rab1a. NAB2 selectively binds to the GDP-bound form of Rab1a and protects multiple cell types from α-synuclein toxicity by increasing Rab1a expression. Rab1a regulates ER-to-Golgi trafficking and mediates endosomal trafficking events of the E3 ubiquitin ligase Rsp5/Nedd4. NAB2 stimulates ubiquitination of related proteins in a Nedd4-dependent manner and rescues α-synuclein-associated trafficking defects associated with early-onset Parkinson's disease .
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Cat. No.: HY-110174R
CAS No.: 1504588-00-4
Research Areas:  

Neurological Disease

NAB2 (Standard) is the analytical standard of NAB2 (HY-110174). This product is intended for research and analytical applications. NAB2 is a neuroprotectant that targets the small GTPase Rab1a. NAB2 selectively binds to the GDP-bound form of Rab1a and protects multiple cell types from α-synuclein toxicity by increasing Rab1a expression. Rab1a regulates ER-to-Golgi trafficKing and mediates endosomal trafficKing events of the E3 ubiquitin ligase Rsp5/Nedd4. NAB2 stimulates ubiquitination of related proteins in a Nedd4-dependent manner and rescues α-synuclein-associated trafficKing defects associated with early-onset ParKinson's disease .
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Cat. No.: HY-P86985
Synonyms: E3 ubiquitin protein ligase Nedd4 like protein antibody; E3 ubiquitin-protein ligase Nedd4-like antibody; KIAA0439 antibody; NED4L_HUMAN antibody; Nedd4 2 antibody; Nedd4-2 antibody; Nedd4 2c antibody; Nedd4-2 antibody; Nedd4-2a antibody; Nedd4.2 antibody; E3 ubiquitin protein ligase Nedd4 like protein antibody; E3 ubiquitin-protein ligase Nedd4-like antibody; KIAA0439 antibody; NED4L_HUMAN antibody; Nedd4 2 antibody; Nedd4-2 antibody; Nedd4 2c antibody; Nedd4-2 antibody; Nedd4-2a antibody; Nedd4.2 antibody; Nedd4b antibody; Nedd4L antibody; Nedd4La antibody; Nedd4Lb antibody; Nedd4Lc antibody; Nedd4Ld antibody; Nedd4Le antibody; Nedd4Lf antibody; Nedd4Lg antibody; Nedd4Lh antibody; NEDL3 antibody; Neural precursor cell expressed developmentally down regulated 4 like E3 ubiquitin protein ligase antibody; Neural precursor cell expressed, developmentally down regulated 4 like antibody; Rsp5 antibody; Ubiquitin protein ligase Rsp5 antibody;

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human

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Cat. No.: HY-P701595
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Nedd4L; Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like; Nedd4 Like E3 Ubiquitin Protein Ligase; HECT-Type E3 Ubiquitin Transferase; HECT-Type E3 Ubiquitin Transferase NED4L; Ubiquitin-Protein Ligase Rsp5; E3 Ubiquitin-Protein Ligas
Species:  
Source:  
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Cat. No.: HY-P701596
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Nedd4L; Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like; Nedd4 Like E3 Ubiquitin Protein Ligase; HECT-Type E3 Ubiquitin Transferase; HECT-Type E3 Ubiquitin Transferase NED4L; Ubiquitin-Protein Ligase Rsp5; E3 Ubiquitin-Protein Ligas
Species:  
Source:  
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