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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
S1 subsites
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "S1 subsites" in MCE Product Catalog:
Cat. No.: HY-139866
CAS No.: 1453052-57-7
SARS-CoV-2-IN-9 is an inhibitor binding to subsites S1 and S2 in SARS-CoV-2 main protease.
Cat. No.: HY-184146
Target:
Research Areas:
AD05 is a SARS-CoV-2 main protease (M pro) inhibitor with an IC50 of 306.5 nM. AD05 exhibits antiviral activity against wild-type SARS-CoV-2 in host cells without inducing significant cytotoxicity. AD05 can be used in studies related to SARS-CoV-2 infection .
Cat. No.: HY-184147
Target:
Research Areas:
AD06 is a SARS-CoV-2 main protease (M pro) inhibitor with an IC50 of 163.3 nM. AD06 undergoes nucleophilic attack by deprotonated Cys145, thereby blocking viral replication. AD06 inhibits the activity of wild-type SARS-CoV-2 and shows no significant cytotoxicity in mammalian cells. AD06 can be used in studies related to SARS-CoV-2 infection .
Cat. No.: HY-182565
CAS No.: 1854997-77-5
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PSI-112 is a YO-class μPlm inhibitor, with IC50 values of 0.38 μM, 1.48 μM and 0.37 μM against the wild-type, F587A mutant and K607A mutant, respectively. PSI-112 shows low affinity for uPA. PSI-112 can be used in cancer research .
Cat. No.: HY-184062
CAS No.: 851220-34-3
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Research Areas:
NI929 is a blood-brain barrier-permeable recombinant mouse aminopeptidase A (APA) inhibitor with a Ki value of 30 nM. NI929 is applicable to research on hypertension and Alzheimer's disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
