2. Metabolic Enzyme/Protease
  3. Plasminogen/Plasmin
  4. PSI-112

PSI-112 is a YO-class μPlm inhibitor, with IC50 values of 0.38 μM, 1.48 μM and 0.37 μM against the wild-type, F587A mutant and K607A mutant, respectively. PSI-112 shows low affinity for uPA. PSI-112 can be used in cancer research.

For research use only. We do not sell to patients.

PSI-112

PSI-112 Chemical Structure

CAS No. : 1854997-77-5

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PSI-112 Related Antibodies

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Description

PSI-112 is a YO-class μPlm inhibitor, with IC50 values of 0.38 μM, 1.48 μM and 0.37 μM against the wild-type, F587A mutant and K607A mutant, respectively. PSI-112 shows low affinity for uPA. PSI-112 can be used in cancer research[1].

IC50 & Target[1]

μPlm

0.38 μM (IC50)

In Vitro

PSI-112 inhibits wild-type μPlm with an IC50 of 0.38 μM, and its affinity for uPA (IC50 >25 μM) is lower than that for μPlm[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PSI-112 Related Antibodies
Molecular Weight

572.78

Formula

C35H48N4O3
CAS No.
SMILES

O=C([C@@H]1CC[C@H](CC1)CN)N[C@H](C(NCCCCCCCC)=O)CC(C=C2)=CC=C2OCC3=NC4=C(C=CC=C4)C=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PSI-112 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PSI-1121854997-77-5PSI112PSI 112Plasminogen/Plasminhuman plasminplasmin catalytic cleftt-cell lymphomaμPlmcolon carcinomaurokinasemPlmS1 subsitesS3' subsitesmelanomaInhibitorinhibitorinhibit

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