4 Results for "

S7958

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "S7958" in MCE Product Catalog:

36
36 Cited Publications
Cat. No.: HY-14927
CAS No.: 170632-47-0
Purity:  99.70%
Synonyms: YC-1
Target:  

Guanylate Cyclase

Research Areas:  

Cardiovascular Disease Cancer

Lificiguat binds to the β subunit of soluble guanylyl cyclase(sGC) with Kd of 0.6-1.1 μM in the presence of CO.
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Cat. No.: HY-139898
CAS No.: 1217341-48-4
Target:  

Taste Receptor

Research Areas:  

Others

S7958 is a selective and orally active antagonist of the TAS2R8 bitter taste receptor, with its IC50 being 0.06 μM. S7958 only has a weak inhibitory effect on TASR8 and TAS2R39, and has no significant impact on other receptors. S7958 significantly inhibits the perception of bitterness caused by substances such as coffee and drug active ingredients (API) by selectively antagonizing the human bitter taste receptor TAS2R8. S7958 can be used in the medical field to improve the research on the bitterness of oral preparations .
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Cat. No.: HY-139899
CAS No.: 1119831-25-2
Target:  

Taste Receptor

Research Areas:  

Others

S6821 is a TAS2R8 antagonist with IC50 value of 0.035 μM. S6821 is not found to be mutagenic or disruptive in vitro, nor is it found to induce micronucleus in bone marrow polychromatic erythrocytes in vivo .
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Cat. No.: HY-14927R
CAS No.: 170632-47-0
Synonyms: YC-1 (Standard)
Lificiguat (Standard) is the analytical standard of Lificiguat. This product is intended for research and analytical applications. Lificiguat binds to the β subunit of soluble guanylyl cyclase(sGC) with Kd of 0.6-1.1 μM in the presence of CO.
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