1 Result for "

SET 0568

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "SET 0568" in MCE Product Catalog:

Cat. No.: HY-171138
CAS No.: 1178887-17-6
Synonyms: SET0568
Research Areas:  

Cancer

Mal-VC-PAB-DMEA-PNU-159682 (SET0568) is an antibody-drug conjugate (ADC) drug-linker conjugate. Mal-VC-PAB-DMEA-PNU-159682 is generated by conjugating the potent anti-topoisomerase II inhibitor PNU-159682 (HY-16700) to the lysosomally cleavable dipeptide Mc-VC-PAB, and exhibits strong antitumor activity. Mal-VC-PAB-DMEA-PNU-159682 can be used to synthesize CD22-targeting ADCs, such as Anti-CD22-NMS249 (HY-164761). Mal-VC-PAB-DMEA-PNU-159682 is also applicable to the research of non-Hodgkin's lymphoma .
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