1 Result for "

SHR902275

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SHR902275" in MCE Product Catalog:

Cat. No.: HY-144269
CAS No.: 2695506-82-0
Target:  

Raf

Research Areas:  

Cancer

SHR902275 is a potent, selective, and orally active RAF inhibitor targeting RAS mutant cancers. SHR902275 has IC50s of 1.6 nM, 10 nM, and 5.7 nM for cRAF, bRAF wt, and bRAF V600E, respectively. SHR902275 shows cell growth inhibition with GI50s of 1.5 and 0.17 nM, 0.4 nM and 0.32 nM for H358, A375, Calu6, and SK-MEL2 cells respectively .
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