4 Results for "

SINE

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "SINE" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-15970
CAS No.: 1392136-43-4
Synonyms: KPT-335
Target:  

CRM1 Apoptosis RSV

Verdinexor (KPT-335) is an orally active inhibitor for selective inhibitor of nuclear export (SINE). Verdinexor inhibits the respiratory syncytial virus A2 (RSV A2) replication with an IC50 of 0.96 µM. Verdinexor inhibits the function of nuclear export protein Exportin 1 (XPO1/CRM1), inhibiting pro-inflammatory responses. Verdinexor exhibits antitumor effciency .
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Cat. No.: HY-17539
CAS No.: 1421919-75-6
Target:  

CRM1

Research Areas:  

Cancer

PKT-276, an analogue of PKT-185, is an oral bioavailable and selective inhibitor of nuclear output (SINE). PKT-276 is also a CRM1 antagonist that irreversibly binds to and blocks the function of CRM1 .
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Cat. No.: HY-164710
Synonyms: b-LMB
Target:  

CRM1

Research Areas:  

Others

Biotinylated leptomycin B is a compound used to quantify nuclear export protein 1 (XPO1) occupancy and is used to study the interaction of SINE compounds with XPO1 and the response of cancer cells to related compounds.
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Cat. No.: HY-P86363
Synonyms: SIX2; Homeobox protein SIX2; SINE oculis homeobox homolog 2

Host:  

Rabbit

Application:  

WB, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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