1421919-75-6
1421919-75-6
Chemical Structure
KPT-276
- CAS No.: 1421919-75-6
- Formula:C16H10F8N4O
- Molecular Weight:426.26
IUPAC Name: (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-1-(3,3-difluoroazetidin-1-yl)prop-2-en-1-one
InChIKey: JCHAWRDHMUSLMM-UPHRSURJSA-N
SMILES: O=C(N1CC(F)(F)C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
Biological Activity: PKT-276, an analogue of PKT-185, is an oral bioavailable and selective inhibitor of nuclear output (SINE). PKT-276 is also a CRM1 antagonist that irreversibly binds to and blocks the function of CRM1[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KPT-276 | 99.94% | PKT-276, an analogue of PKT-185, is an oral bioavailable and selective inhibitor of nuclear output (SINE). PKT-276 is also a CRM1 antagonist that irreversibly binds to and blocks the function of CRM1. | ||||||||||||||||||||
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References
Keywords
