1 Result for "

SLMP53-2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SLMP53-2" in MCE Product Catalog:

Cat. No.: HY-153202
CAS No.: 1826116-38-4
Purity:  99.96%
Target:  

MDM-2/p53 Apoptosis

Research Areas:  

Cancer

SLMP53-2 is a mutant p53 reactivator. SLMP53-2 restores wild-type-like conformation and DNA-binding ability of mutp53-Y220C by enhancing its interaction with the Hsp70, leading to the reestablishment of p53 transcriptional activity. SLMP53-2 can induce cell cycle arrest, apoptosis and endoplasmic reticulum (ER) stress. SLMP53-2 exhibits antitumor activity .
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