1 Result for "

SM311

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SM311" in MCE Product Catalog:

Cat. No.: HY-174229
Target:  

LIM Kinase (LIMK)

Research Areas:  

Neurological Disease Cancer

SM311 (Compound 10), a chemical probe, is a potent selective irreversible LIMK1 inhibitor (EC50=0.045 μM, >30-fold selective over LIMK2). SM311 blocks cofilin phosphorylation and actin cytoskeleton regulation. SM311 is promising for research of neurodegenerative diseases like Fragile X syndrome (FXS) and Alzheimer’s disease, as well as tumor invasion .
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