1 Result for "

SMD6346

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SMD6346" in MCE Product Catalog:

Cat. No.: HY-184673
CAS No.: 3086248-19-0
Target:  

PROTACs SWI/SNF Complex

Domaines de recherche:  

Cancer

SMD-6346 is an orally active SMARCA2 PROTAC degrader with a DC50 of 3.3 nM. SMD-6346 induces SMARCA2 degradation and exhibits extremely low activity against SMARCA4. SMD-6346 inhibits the growth of SMARCA4-deficient cancer cells and suppresses tumor growth in mouse xenograft models. SMD-6346 can be used for the research of non-small cell lung cancer .
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