1 Result for "

SPRi 3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SPRi 3" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-115510
CAS No.: 1292285-54-1
Purity:  99.84%
Synonyms: SPRi3
Target:  

Carbonyl Reductase

Research Areas:  

Inflammation/Immunology

SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels .
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