1 Result for "

SRI35241

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SRI35241" in MCE Product Catalog:

Cat. No.: HY-182612
CAS No.: 2307429-54-3
Target:  

TGF-β Receptor

Research Areas:  

Cancer

SRI-35241 is a thrombospondin TSP-1 inhibitor with a pIC50 of 8.12 nM against human targets. SRI-35241 inhibits the binding of TSP-1 to latent transforming growth factor-β-associated peptide (LAP) and blocks the activation of TGF-β. SRI-35241 shows a certain time-dependent property, with a plasma half-life of 1.8 h after intravenous administration. SRI-35241 can be used for the research of multiple myeloma and fibrotic diseases .
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