2 Results for "

SSR-180711

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "SSR-180711" in MCE Product Catalog:

Cat. No.: HY-167824
CAS No.: 298198-52-4
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

SSR180711 is a potent and subtype-selective α7 agonist with activity in Alzheimer's disease and schizophrenia research. SSR180711 can be used to study subtypes of intracerebral hemorrhage associated with cerebral small vessel disease. SSR180711 shows potential in electrophysiological and behavioral studies to evaluate its effects on cognitive function. SSR180711 also has potential for studying cerebrovascular lesions and their effects .
loading...
    loading...
Cat. No.: HY-19411
CAS No.: 446031-79-4
Target:  

nAChR

Research Areas:  

Neurological Disease

SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 hydrochloride can act on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long-term potentiation (LTP) in the hippocampus .
loading...
    loading...