446031-79-4
Chemical Structure
SSR180711 hydrochloride
- CAS No.: 446031-79-4
- Formula:C14H18BrClN2O2
- Molecular Weight:361.66
IUPAC Name: 4-bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate hydrochloride
InChIKey: YNBXNVUZXFMNSJ-UHFFFAOYSA-N
SMILES: O=C(N1CCN2CCC1CC2)OC3=CC=C(Br)C=C3.[H]Cl
Biological Activity: SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 hydrochloride can act on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long-term potentiation (LTP) in the hippocampus[1].
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SSR180711 hydrochloride | 99.90% | SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 hydrochloride can act on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long-term potentiation (LTP) in the hippocampus. | ||||||||||||||||||||
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Keywords
