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Results for "

SUR2A

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-120158
    ZD0947

    		Potassium Channel Neurological Disease
    ZD0947 is an ATP-sensitive potassium channel activator with relatively effective activation of smooth muscle KATP channels (SUR2B/Kir6.1 and SUR2B/Kir6.2). ZD0947 partially antagonizes pancreatic KATP channels (SUR1/Kir6.2) and cardiac KATP channels (SUR2A/Kir6.2). ZD0947 is potentially used to inhibit overactive bladder (OAB) .
    ZD0947
  • HY-15210
    Meglitinide

    		Potassium Channel Metabolic Disease
    Meglitinide is an ATP-sensitive potassium (KATP) channel inhibitor. Meglitinide exhibits IC50 values of 0.26 μM, 0.53 μM and 1.6 μM against KATP channels containing SUR1, SUR2A and SUR2B, respectively, with a Kd value of 7 μM for both SUR1 and SUR2A, and a Kd value of 8 μM for SUR2B. Meglitinide binds to the SUR1, SUR2A and SUR2B subunits with high affinity to close KATP channels, acting on a binding site shared by all SUR subtypes, and its interaction with SUR1 carrying the S1237Y mutation remains unchanged. Meglitinide is applicable to research related to type 2 diabetes .
    Meglitinide
  • HY-RS22364
    Abcc9 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Abcc9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Abcc9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Abcc9 Mouse Pre-designed siRNA Set A
    Abcc9 Mouse Pre-designed siRNA Set A

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