1 Result for "

Secoverine

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Secoverine" in MCE Product Catalog:

Cat. No.: HY-183540
CAS No.: 57558-44-8
Target:  

mAChR

Secoverine is a muscarinic cholinergic receptor (mAChR) antagonist and antispasmodic with blood-brain barrier permeability. Secoverine binds competitively to muscarinic receptors, blocks central cholinergic effects, and inhibits cholinergically induced gastrointestinal motility, intestinal smooth muscle contraction, and acetylcholine-mediated neurotransmitter release. Secoverine exerts direct antispasmodic activity on intestinal smooth muscle independent of receptor blockade, and exhibits characteristics such as reversible smooth muscle activity and long duration of action. Secoverine can be used in studies related to hyperintestinal motility, diverticular disease, and colonic spasm .
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