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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Streptavidin pull-down
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Streptavidin pull-down" in MCE Product Catalog:
223
223 Cited Publications
Cat. No.: HY-K0208
MCE Streptavidin Magnetic Beads provide a fast and convenient method for numerous applications, including purification of proteins and nucleic acids, protein interaction studies, immunoprecipitation, immunoassays, pull-down and cell isolation. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
Cat. No.: HY-101974
CAS No.: 1041766-91-9
Cat. No.: HY-W130607
CAS No.: 1238575-77-3
Target:
Research Areas:
Biotinyl-8-amino-3,6-dioxaoctanoic acid is a biotinylating reagent linked with a PEG chain for improved water solubility. Biotin is an affinity ligand and it is used in biochemical applications such as pull-down assays or for ligating with streptavidin proteins. The carboxylic group can react with amine-containing molecules in the presence of activators such as HATU.
Cat. No.: HY-186233
Research Areas:
CS-1-174 is a biotin-modified probe derived from KCC-07 (HY-131031), with specific binding activity to enrich MBD2. CS-1-174 captures MBD2 in cell lysates via pull-down by binding streptavidin magnetic beads through its terminal biotin tag. CS-1-174 serves as a functional tool probe in the development of TRACER technology, and is used to verify the target binding ability of MBD2 in tumor cells .
Cat. No.: HY-18542
CAS No.: 1402612-58-1
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
KT195 is a serine hydrolase inhibitor that targets ABHD6 (IC50 = 10 nM) and ABHD2, with no significant activity against DAGLβ. KT195 inhibits endoplasmic reticulum calcium release and mitochondrial calcium uptake by targeting ABHD2, thereby blocking A23187 (HY-N6687) and H2O2-induced necrotic cell death and apoptosis. By inhibiting ABHD6 activity, KT195 significantly induces 2-AG accumulation in Neuro2A cells and reduces IL-1β secretion in lipopolysaccharide-treated macrophages. KT195 has been used as a negative control probe for DAGLβ and can be applied in studies of ABHD6 and ABHD2 in calcium signaling, lipid metabolism, neuronal function, and inflammatory .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
