2 Results for "

Systemic adverse effects

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Systemic adverse effects" in MCE Product Catalog:

Cat. No.: HY-124098
CAS No.: 2903-45-9
Purity:  99.92%
Synonyms: Lidocaine N-oxide
Research Areas:  

Cardiovascular Disease

Lignocaine N-oxide (Lidocaine N-oxide) is a hypoxia-activated prodrug of lidocaine (HY-B0185). Lignocaine N-oxide exerts exactly the same sodium current-blocking effect as lidocaine only when it is converted to lidocaine under ischemic conditions. Lignocaine N-oxide possesses antiarrhythmic activity against ischemia-induced ventricular fibrillation. Lignocaine N-oxide can be used in studies related to ischemia-induced ventricular fibrillation .
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Cat. No.: HY-145829
Target:  

JAK Apoptosis

Research Areas:  

Inflammation/Immunology

Tofacitinib precursor-1 is an effective and oral active precursor to mitigate the systemic adverse effects of Tofacitinib. Tofacitinib precursor-1 can effectively attenuate the oxazolone-induced colitis in mice model with low toxicity. Tofacitinib precursor-1 is a potential drug candidate for the research of ulcerative colitis .
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