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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
TD428
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "TD428" in MCE Product Catalog:
Target:
Research Areas:
TD-428 is a PROTAC connected by ligands for Cereblon and BRD4. TD-428 is a highly specific BRD4 degrader with a DC50 of 0.32 nM . TD-428 is a BET PROTAC, which comprises TD-106 (a CRBN ligand) linked to JQ1 (a BET inhibitor). TD-428 efficiently induce BET protein degradation .
Cat. No.: HY-184562
CAS No.: 2324144-03-6
Research Areas:
TD-106-PEG3-aniline (Compound 17b) is an aminobenzotriazinyl glutarimide analog that binds to cereblon (CRBN). Equipped with a PEG3 linker and an aniline group, TD-106-PEG3-aniline serves as a E3 ligase ligand-Linker conjugates for the synthesis of PROTAC TD-428 (HY-114407) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
