TD-106-PEG3-aniline
TD-106-PEG3-aniline (Compound 17b) is an aminobenzotriazinyl glutarimide analog that binds to cereblon (CRBN). Equipped with a PEG3 linker and an aniline group, TD-106-PEG3-aniline serves as a E3 ligase ligand-Linker conjugates for the synthesis of PROTAC TD-428 (HY-114407).
For research use only. We do not sell to patients.
- CAS No.: 2324144-03-6
- Formula: C24H28N6O6
- Molecular Weight:496.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Target protein ligand-linker conjugates combine ligands of target proteins with linkers. When bound to E3 ligase ligands, these conjugates become PROTACs that can induce ubiquitination and subsequent degradation of target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2324144-03-6
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Molecular Weight 496.52
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Formula C24H28N6O6
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SMILES
NC1=CC(OCCOCCOCCNC2=C3C(N=NN(C(CC4)C(NC4=O)=O)C3=O)=CC=C2)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TD-106-PEG3-aniline Related Classifications
HY-184562 Related Classifications
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