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Results for "

TEV

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Peptides

3

Inhibitory Antibodies

1

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P990006

    TEV-48574; SAR-447189; TEV-574

    TNF Receptor Inflammation/Immunology
    Duvakitug (TEV-48574) is a humanized IgG1-λ2 monoclonal antibody targeting to TNFSF15/TL1A. Duvakitug' main expression system is CHOK1SV cells endogenously expressing glutamine synthetase (GS). Duvakitug can be used in the study of Crohn's Disease (CD) .
    Duvakitug
  • HY-P99019
    Fremanezumab
    2 Publications Verification

    TEV-48125; LBR-101; PF-04427429; RN-307

    CGRP Receptor Neurological Disease Inflammation/Immunology
    Fremanezumab (TEV-48125) is a humanized lgG2 monoclonal antibody that selectively and potently binds to calcitonin gene related peptide (CGRp) (IC50 values = 7.943 nM). Fremanezumab binds to mouse CGRP with an IC50 value of 19.6 nM. Fremanezumab counteracts anti-inflammatory effects of CGRP in vitro, including CGRP-mediated inhibition of LPS (HY-D1056)-induced microglial activation. Fremanezumab selectively inhibits the activation of Aδ meningeal nociceptors by cortical spreading depression (CSD) in rats. Fremanezumab can be used for the study of inflammation and chronic migraine .
    Fremanezumab
  • HY-P10871

    Virus Protease Infection
    cTEV6-2 binds to the cysteine residue (C151) of tobacco etch virus protease (TEV protease), and covalently inhibits TEV protease with an IC50 of 81.7 nM .
    cTEV6-2
  • HY-P990058

    Interleukin Related Inflammation/Immunology
    Varokibart (TEV-53275) is a human IgG4λ antibody targeting IL5 .
    Varokibart
  • HY-W736950

    Insecticide Others
    HL-Cys(MDNPE)-OH (compound 2) is a genetically encoded photocaged cysteine compound that has the activity to activate TEV protease upon light exposure in mammalian cells.
    H-L-Cys(MDNPE)-OH

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