6 Results for "

TEV

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "TEV" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99019
CAS No.: 1655501-53-3
Synonyms: TEV-48125; LBR-101; PF-04427429; RN-307
Fremanezumab (TEV-48125) is a humanized lgG2 monoclonal antibody that selectively and potently binds to calcitonin gene related peptide (CGRp) (IC50 values = 7.943 nM). Fremanezumab binds to mouse CGRP with an IC50 value of 19.6 nM. Fremanezumab counteracts anti-inflammatory effects of CGRP in vitro, including CGRP-mediated inhibition of LPS (HY-D1056)-induced microglial activation. Fremanezumab selectively inhibits the activation of Aδ meningeal nociceptors by cortical spreading depression (CSD) in rats. Fremanezumab can be used for the study of inflammation and chronic migraine .
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1
1 Cited Publications
Cat. No.: HY-P990006
CAS No.: 2750005-84-4
Synonyms: TEV-48574; SAR-447189; TEV-574

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

Duvakitug (TEV-48574) is a humanized IgG1-λ2 monoclonal antibody targeting to TNFSF15/TL1A. Duvakitug' main expression system is CHOK1SV cells endogenously expressing glutamine synthetase (GS). Duvakitug can be used in the study of Crohn's Disease (CD) .
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Cat. No.: HY-P10871
Target:  

Virus Protease

Research Areas:  

Infection

cTEV6-2 binds to the cysteine residue (C151) of tobacco etch virus protease (TEV protease), and covalently inhibits TEV protease with an IC50 of 81.7 nM .
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Cat. No.: HY-P990058
CAS No.: 2643349-04-4

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Varokibart (TEV-53275) is a human IgG4λ antibody targeting IL5 .
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Cat. No.: HY-W736950
CAS No.: 1551078-43-3
Target:  

Insecticide

Research Areas:  

Others

HL-Cys(MDNPE)-OH (compound 2) is a genetically encoded photocaged cysteine compound that has the activity to activate TEV protease upon light exposure in mammalian cells.
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Cat. No.: HY-P79151A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Genome polyprotein; Tobacco Etch Virus Protease
Species:  
Source:  
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